Wantirna South is a suburb of Melbourne, Victoria, Australia, located 28km east of Melbourne’s Central Business District. Its local government area is the City of Knox. At the 2016 Census, Wantirna South had a population of 16,945.

Wantirna South is a residential suburb with a mix of housing styles, including single-family homes, townhouses, and apartments. The suburb is home to a number of parks and reserves, including the Wantirna South Recreation Reserve, which features a playground, sports fields, and a walking track. The suburb also has a shopping centre, Wantirna Mall, which includes a supermarket, specialty stores, and a cinema.

Wantirna South is well-connected to the rest of Melbourne, with a number of bus routes running through the suburb and a train station located nearby in neighbouring Wantirna. The EastLink freeway also runs through the suburb, providing easy access to the city and other parts of Melbourne.